Preclinical PET Neuroimaging of [11C]Bexarotene
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چکیده
منابع مشابه
Preclinical PET Neuroimaging of [11C]Bexarotene
Activation of retinoid X receptors (RXRs) has been proposed as a therapeutic mechanism for the treatment of neurodegeneration, including Alzheimer's and Parkinson's diseases. We previously reported radiolabeling of a Food and Drug Administration-approved RXR agonist, bexarotene, by copper-mediated [(11)C]CO2 fixation and preliminary positron emission tomography (PET) neuroimaging that demonstra...
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ژورنال
عنوان ژورنال: Molecular Imaging
سال: 2016
ISSN: 1536-0121,1536-0121
DOI: 10.1177/1536012116663054